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Strategies
August 26, 2022
Substance use prevention and treatment

Strategy overview

    • Creating a continuum of care: Local governments and community-based organizations play a vital role in addressing the nationwide addiction and overdose crisis. Evidence-based approaches typically treat addiction as a chronic recurring illness and include comprehensive prevention, harm reduction, treatment, and post-recovery programs. These interventions aim to lower the risk of substance use, particularly among vulnerable populations such as teens; minimize the negative impacts (harm reduction) to individuals and communities associated with substance use; and provide a range of evidence-based treatment models. In addition, post-treatment support services help residents find jobs, housing, and continuing access to peer counseling services.

    • Expanding prevention and raising risk awareness: Research shows that 9 in 10 cases of drug addiction start before age 18. Substance use often begins during times of stress, such as school transitions, and is heavily influenced by peer pressure, social media, family dynamics, socioeconomic factors, and more. Effective prevention should, therefore start before a person’s first use of a mind-altering substance. Programs can begin as early as middle school and continue through high school, college, and into young adulthood. In addition to programs that take place at and after school, apt settings may include recreation centers, healthcare facilities, and other community spaces serving youth.

    • Increasing the scope of harm reduction: Unlike incarceration and mandatory treatment models, harm reduction seeks to “meet users where they are” to maintain their health, safety, and social well-being. Program goals typically include the distribution of sterile syringe supplies to reduce the transmission of infectious diseases related to intravenous drug use; drug testing strips to detect illicitly manufactured fentanyl, which is responsible for two-thirds of all drug-related deaths; and ensuring that the overdose reversal medication naloxone is widely available and administered properly. Studies show that harm reduction interventions can be effective as part of a broader suite of services, including counseling and motivational peer support. Harm reduction aims to build trust with participants and encourages them to enter treatment, although this is not required to receive services. Novel harm reduction initiatives such as overdose prevention centers in New York City provide a safer, indoor environment in which to use substances with medical personnel on hand to administer life-saving measures if necessary.

    • Prioritizing treatment: Studies show that a range of evidence-based treatment models can be highly effective in helping people reduce substance use and address associated medical, psychological, and social problems. Jurisdictions can offer options that include outpatient and short- and long-term residential care, often using medications for opioid use disorder (MOUD) that employ medications like methadone and buprenorphine to reduce cravings and support behavioral therapies. Studies show that MOUD is highly successful, especially in treating opioid use disorder. Another approach is the substance-free abstinence model (i.e. Narcotics Anonymous), which can be effectivefor certain people who use drugs.

Multiple comprehensive research reviews of foundational practices in treating and preventing substance use demonstrated strong evidence of reduced drug use and recidivism and increased public safety.

  • 2016 research reviews of individual and family treatment drug courts found the model is associated with reductions in drug-related and general recidivism, increases in completed addiction treatment, and increases in the likelihood of family unification.

  • A 2021 research synthesis of multiple rigorous evaluations found strong evidence that community-based safe syringe service programs can reduce injection risk behavior and HIV transmission. A 2024 National Institute on Drug Abuse article notes the health, safety, and cost benefits of syringe services programs (SSPs).   

  • A 2024 CDC article explains that syringe services programs (SSPs) do not increase illegal drug use or crime and reduce needle stick injuries suffered by emergency services personnel. 

  • A 2018 research synthesis of multiple rigorous evaluations found strong evidence that integrating behavioral health — including drug screens — into primary care visits can reduce drug and alcohol use, increase adherence to treatment plans, and improve mental health outcomes.

  • A 2025 research report documents how to most effectively use medications for addiction treatment. A 2024 study of a take-home methadone program and accompanying app found that participants benefitted from the autonomy offered by take-home methadone devices and made recovery more attainable by not having to routinely check in at clinics to receive treatment.

Before making investments in substance use treatment and prevention programs, city and county leaders should ensure this strategy addresses local needs.

The Urban Institute and Mathematica have developed indicator frameworks to help local leaders assess conditions related to upward mobility, identify barriers, and guide investments to address these challenges. These indicator frameworks can serve as a starting point for self-assessment, not as a comprehensive evaluation, and should be complemented by other forms of local knowledge.

The Urban Institute's Upward Mobility Framework identifies a set of key local conditions that shape communities’ ability to advance upward mobility and racial equity. Local leaders can use the Upward Mobility Framework to better understand the factors that improve upward mobility and prioritize areas of focus. Data reports for cities and counties can be created here.

Several indicators in the Upward Mobility Framework may be improved with investments in high-quality substance use treatment and prevention programs. To measure these indicators and determine if investments in this strategy could help, examine the following:

Mathematica's Education-to-Workforce (E-W) Indicator Framework helps local leaders identify the data that matters most in helping students and young adults succeed. Local leaders can use the E-W framework to better understand education and workforce conditions in their communities and to identify strategies that can improve outcomes in these areas.

Several indicators in the E-W Framework may be improved with investments in this strategy. To measure these indicators and determine if investments in this strategy could help, examine the following:

  • Flexible service delivery: Substance use treatment and prevention programs must be delivered in a mode that is accessible to all participants. Depending on circumstances, this could include on-site facilities (particularly necessary in the case of medication delivery), or virtually or by telephone when in-person meetings are not possible. Mobile options, like mobile narcotics programs such as methadone vans and vending machines that dispense harm reduction supplies, provide easier delivery, especially for marginalized populations that face difficulties accessing care. Flexible delivery may be particularly important in rural contexts or in Native American communities that have experienced high rates of substance use and overdose.

  • Address multiple risk factors: Prevention programming should be developed around the risk factors and root causes associated with drug use. Programming should inform residents about drug harms and provide protective measures and support. Target environmental factors (such as access to alcohol or other drugs) and individuals at risk (including those who have experienced peer pressure, adverse childhood experiences, and family drug use). Experts say programs should also consider socioeconomic factors such as poverty and financial hardship and emphasize developing life skills, academic success, and family management. Prevention outreach should extend to community-based services for out-of-school youth who may be experiencing housing instability.

  • Tailored to participant needs or circumstances: Interventions and programming should be tailored to meet the needs and experiences of particular people, including those of different races, ethnicities, ages, and life experiences. These may include adolescents who have lost a parent to drug use, pregnant women, and mothers who want to remain with their children while in treatment. Other target demographics that may benefit from tailored programming are people 55 or older who use substances, the LGBTQ+ community, and individuals with mental health issues. Successful youth programming may focus on building confidence and social-emotional skill development through education, sports, the arts, and more.

  • Wraparound services: Successful substance use treatment programs typically incorporate wraparound services to support individuals through the recovery process. Post-recovery services can include job and vocational training, housing assistance and placement, and continued access to peer counseling. Some models focus on recovery-based housing accommodations and programs to establish recovery-friendly workplaces that are stigma-free and welcoming to individuals re-entering the workforce.

  • Peer support: A critical support mechanism of recovery is peer counseling from individuals who have gone through similar addiction experiences and recovery processes. Through shared understanding and respect, peer counselors working with individuals or in groups can reduce the likelihood of relapse and extend the reach of treatment beyond a clinical setting into the daily environment of the patient.

  • Build trust and respect for the individual: Experts say substance use services should help individuals take the first step toward reducing drug use, entering treatment, and eventually navigating recovery. This requires understanding an individual’s unique path to recovery, which oftentimes involves frequent setbacks and recurrence of use. Interventions should be designed to build trust with residents to bring them into the treatment and recovery community, emphasizing improving health and well-being, family relationships, and vocational responsibility.

  • Hire staff with adequate cultural competency: Programs should prioritize hiring staff that represent the communities they serve, have lived experiences in common with those they engage with, and recognize cultural sensitivities that may be at play. Given the history of harm and marginalization many communities have experienced during the decades-long “war on drugs” and in healthcare institutions, participants may be hesitant to engage with services.

  • Distribute services equitably: Services should not only be distributed in alignment with current needs but also in a manner that redresses historical inequities in access to treatment. This is particularly critical given the recent significant increases in drug use and overdose among Black, Hispanic, and Native American populations. Experts also encourage placing substance use treatment services in homeless shelters, mental health facilities, and other locations that provide care to those with overlapping conditions.

  • Language access: Given the scope of the addiction and overdose crisis across races and ethnicities, it is important to ensure that services are available in multiple languages. This can make it easier for users to understand treatment protocols, ease fears of entering treatment, and build trust between healthcare providers and patients.

  • Prevention advocates: Creating a multi-sector coalition of prevention advocates can help ensure that programs are comprehensive, culturally aware, and reaching the right people. A prevention coalition might include leaders from health systems, education, law enforcement, and community-based organizations.

  • Substance use organizations and healthcare agencies: To ensure that all individuals in need are reached, social service agencies, healthcare institutions, and recovery and treatment organizations should coordinate their activities. This coordination can also help identify potential gaps in services.

  • Law enforcement: Given law enforcement’s role in monitoring drug flows and carrying out interdiction, federal law enforcement agencies and local police are in a position to inform health providers and substance use agencies about potentially lethal drugs on the market and the drug hotspots where they are sold. They can also issue alerts about the presence of fentanyl and fentanyl-laced counterfeit drugs that users take unwittingly and may cause overdose.

  • Community-based organizations: Many communities, including those of color, have suffered disproportionately from the drug crisis. To secure buy-in from residents about programs such as harm reduction, which maintain a drug presence in communities and can, therefore, be controversial, inform residents about the benefits these may provide for individuals and communities. Experts note that harm reduction programs can reduce not only drug use but also street crime and are associated with fewer overdose deaths.

  • Government leaders: Because some innovative drug policies go against long-held public beliefs about the nature of addiction, prevention, and treatment, support from elected leaders can be difficult to secure. Engaging political leaders is essential for creating buy-in on both funding (including newly available monies from the national opioids settlement) and staffing for pilot programs and expansions to existing services.

  • Open pathways to treatment: Only a small percentage of individuals with substance use disorder receive treatment, often due to lack of insurance, distance from a treatment facility, and concerns about the difficulties of recovery. Public health departments, treatment centers, and community-based organizations can help residents obtain financial support (i.e., Medicaid), find transportation in both urban and rural settings, and receive peer counseling to encourage entry into treatment. Meanwhile, harm reduction programs, which do not mandate treatment, also play a role by providing a nonjudgmental environment in which to build trust with patients to move them into treatment when they are ready.

  • Consider diversion: Jurisdictions can facilitate the reduction of drug use and access to treatment in a legal setting, such as drug courts, which operate in all 50 states and combine treatment with incentives and sanctions as tools to improve health and public safety. Offenders with a drug dependency are given the option of diversion from jail to clinical treatment and offered other supports. Another model diverts drug offenders before they enter the criminal justice system and places them in treatment programs. Studies show that drug courts can reduce drug use and re-arrest, especially in more complex cases in which the individual has not responded to other interventions. 

  • Strengthen regulations: Community-wide solutions to substance use can include legislation, such as regulating alcohol outlet density or raising alcohol and marijuana taxes in jurisdictions where recreational and medical cannabis are legal. Other measures in these communities may include better oversight of underage consumption and unlicensed retail cannabis operations, mandates requiring warning labels for certain groups, such as pregnant women, and restrictions on the level of THC, the psychoactive component of marijuana, which in strong doses can lead to cannabis use disorder and other negative impacts.

  • Overdose rates and causes: With more than 1 million people having been killed in drug-related overdoses in the U.S. since 2000 and upwards of 100,000 fatalities annually, jurisdictions must track the progression of overdoses closely. In addition, healthcare providers and social service agencies need to know as precisely as possible the cause of each overdose, or if multiple drugs were involved, due to increased polysubstance use.

  • Participant demographics: Collecting data concerning race, ethnicity, gender, and age of drug users and overdose victims is standard practice and can help service providers target priority populations with specialized services and outreach. Jurisdictions can design more targeted education and prevention programs based on affected populations and their needs and also determine the best locations for detox, harm reduction, and treatment facilities that are closest to residents.

  • Harm reduction impact: For harm reduction services to gain more traction and support from elected officials and communities, advocates need data showing the extent to which programs reduce drug use and street crime, contain the spread of infectious diseases, mitigate the overdose rate, and facilitate individuals entering treatment. Experts point out that research is just beginning to track new overdose prevention centers and their impact on overdose rates, treatment referrals, and treatment entries.

  • Broader trends: Surveillance surveys provide data on risk factors, consumption rates, mental health, addiction, and more. Examples include the Youth Risk Behavior Survey (YRBS) and the Behavioral Risk Factor Surveillance System (BRFSS), which track substance use based on the past month's use of alcohol, marijuana, etc.

Evidence-based examples

Local regulations to limit the number of establishments in a given area that sell or serve alcohol
Supportive neighborhoods Stable and healthy families
Proven
Incarceration alternative requiring supervision, drug treatment and testing, and sanctions for drug offenders
Stable and healthy families Supportive neighborhoods
Strong
Incarceration alternative including substance abuse testing, judicial monitoring, and support services to parents of children in the child welfare system
Stable and healthy families Supportive neighborhoods
Proven
Connecting at-risk youth to mentors who promote safe and healthy behavior
High school graduation Supportive neighborhoods

Evidence varies across specific models

Community-based programs that provide access to sterile needles, syringes, and other injection equipment
Supportive neighborhoods
Proven
Curriculum to develop social skills, positive character traits, and nonviolent and drug-free norms among K-12 students
High school graduation Supportive neighborhoods
Proven

Contributors

Dr. Brandon Marshall

Dr. Brandon Marshall is a Professor of Epidemiology at the Brown University School of Public Health and the Founding Director of the People, Place & Health Collective (PPHC) at Brown University. He is the Principal Investigator of multiple NIH-funded projects, including the Rhode Island Prescription and Injection Drug Use Study (RAPIDS) and PROVIDENT, a randomized trial to prevent overdose deaths in Rhode Island. He is also the Scientific Director of PreventOverdoseRI, Rhode Island's drug overdose surveillance and information dashboard.

Dr. Peter Provet

Dr. Peter Provet has been the President and CEO of Odyssey House since 1999, leading one of New York City’s largest non-profit organizations dedicated to substance use and mental health treatment. Under his leadership, Odyssey House has developed comprehensive programs for special populations, including women and children (allowing mothers to receive treatment alongside their children), seniors, and people with mental illness. Additionally, Odyssey House offers supportive housing options for homeless families and single adults, facilitating a stable environment for long-term recovery. Dr. Provet holds a doctorate in Clinical Psychology from Boston University and is a licensed clinical psychologist with over 30 years of clinical experience.

Rodney Wambeam, Ph.D

Rodney Wambeam, Ph.D. is a Senior Research Scientist at the Wyoming Survey & Analysis Center of the University of Wyoming. Dr. Wambeam was the principal investigator of Wyoming’s SIG and SPF SIG evaluations and is currently the principal investigator of Wyoming’s Prevention Block Grant and PFS evaluations as well as Oregon’s SPF SIG evaluation. He is also the Director of the Mountain Plains Prevention Technology Transfer Center, Region 8 PTTC.